Cardinals stun Rams as Eagles lose Hurts – five takeaways from NFL week six
The sixth week of the NFL season delivered a series of headline‑making moments. Philadelphia’s quarterback Jalen Hurts was diagnosed with multiple blood clots in his lungs and is expected to miss the remainder of the campaign, while the Arizona Cardinals pulled off the biggest upset of the year by defeating the Los Angeles Rams. Other notable stories include the Chiefs’ continued unbeaten run, the Browns’ surprising start, and a thrilling London finale that saw the Houston Texans edge the Jacksonville Jaguars.
Eagles lose Hurts for the season
Philadelphia entered the weekend already dealing with a rash of injuries, including the loss of offensive linemen Lane Johnson, who retired, and Cam Jurgens, who was traded to Baltimore. After a loss to Jacksonville at Tottenham, the team disclosed that Hurts had played with a superficial clot in his calf. An ultrasound later showed the clot had traveled, prompting backup Tanner McKee to start his third NFL game against the Carolina Panthers. Tommy Tremble caught his first two touchdowns of the year as the Panthers won 25‑14, sending the Eagles to a fourth straight defeat – the first such streak since head coach Nick Sirianni arrived in 2021. On Monday, doctors confirmed Hurts suffers from deep‑vein thrombosis and bilateral pulmonary emboli, meaning multiple clots in his lungs. The 2025 Super Bowl MVP is now undergoing treatment and, according to NFL Network’s Ian Rapoport, will be out for at least three months, effectively ending his season. Fans in Philadelphia worry that the loss of their star quarterback may signal the close of a recent era of success.
Cardinals pull off surprise win over Rams
The Los Angeles Rams entered the season as the most obvious Super Bowl favorite in nine years, but a recent overtime loss to the Buffalo Bills has dropped them behind the San Francisco 49ers. After cutting kicker Harrison Mevis, the Rams signed Blake Grupe from the New York Jets’ practice squad. Grupe opened the scoring against Arizona but injured his knee on a tackle during the ensuing kickoff. With punter Ethan Evans handling the extra point after Colby Parkinson’s touchdown, the Rams led 16‑15 with 47 seconds left. Arizona responded with a career‑high sixth field goal by Chad Ryland, sealing an 18‑16 victory as time expired. The Cardinals, who have now won two of their first two games – both at SoFi Stadium, including a week‑one win over the Los Angeles Chargers – moved ahead of the Rams in the NFC West, a division that also contains the unbeaten 49ers and defending champion Seattle Seahawks. Rams head coach Sean McVay said the team must figure things out, beginning with himself.
Chiefs keep perfect record, Mahomes ties Brady
Patrick Mahomes recorded his 100th regular‑season win in his 131st start, matching Tom Brady’s career total. After missing the playoffs last year, Kansas City bolstered its roster by signing Super Bowl MVP Kenneth Walker, who rushed for 128 yards and two touchdowns in a 22‑6 victory over the Los Angeles Chargers. Walker now leads the league with 665 rushing yards, the most a player has accumulated in his first five games with a new team. The Chiefs, now 5‑0, will travel to Seattle next Sunday to face former teammate Russell Wilson’s Seahawks. The Minnesota Vikings share the unbeaten 5‑0 mark, while the 49ers remain the only team at 6‑0 after a 23‑17 win over Washington.
Other league highlights
The Buffalo Bills improved to 5‑1 after a 33‑30 win at the Las Vegas Raiders. In Atlanta, Caleb Williams returned from a hamstring injury to help the Chicago Bears defeat the Falcons 31‑23.
Travis Hunter records rare two‑way feat in London
The Jacksonville Jaguars stayed in London to meet the Houston Texans after a dramatic win over the Eagles the previous week. The high‑scoring contest, the highest‑point total in a London game since 2015, ended 34‑31 in Houston’s favor thanks to a field goal by Ka’imi Fairbairn. Jacksonville’s Travis Hunter, the No. 2 overall pick in the 2025 draft, sought to become the league’s first full‑time two‑way player in three decades. In his 13th NFL game, the 23‑year‑old wide receiver and cornerback caught a touchdown pass and intercepted a pass in the same game – the first such combination since Brian Dawkins in 2002 and only the fourth since the 1970 merger. Both plays came in the fourth quarter; his interception set up a Cam Little field goal that tied the game at 31‑31 before Fairbairn’s kick gave Houston the win and dropped the Jaguars to 4‑2.